DrugRepV Browse Page


DrugRepV browse page allows user to take a glance of the particular antiviral agent.Fields in the webpage is hylerlinked ot various external repositories like DrugBank, PubChem, Clinicaltrials.gov,and PubMed.User can explore the biological, Clinical, Chemical, and Structural details of every repurposed drug candidate.By clicking on the table header arrows, user can sort entries in ascending or descending order.


Total number of Records for CatL-Peptide cleavage are 150




DrugRepV_ID Antiviral Name
Drug type
Primary Indication
Secondary Indication
Strain
Pathways
Assay
Activity
Clinical Status
References
DrugRepV_4321N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (44.6 %)
NA
24501399
DrugRepV_4322N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (32.6 %)
NA
24501399
DrugRepV_43239H-carbazol-3-amine
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (6.1 %)
NA
24501399
DrugRepV_43247-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-3.8 %)
NA
24501399
DrugRepV_4325N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-16 %)
NA
24501399
DrugRepV_4326tris[4-(dimethylamino)phenyl]methanol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (31.8 %)
NA
24501399
DrugRepV_43276-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (31.8 %)
NA
24501399
DrugRepV_43281-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-1.6 %)
NA
24501399
DrugRepV_43292-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-1.8 %)
NA
24501399
DrugRepV_4330N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (66.3 %)
NA
24501399
DrugRepV_43314-{[(5-methyl-2-thienyl)methyl]amino}phenol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-12.6 %)
NA
24501399
DrugRepV_4332N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-3.4 %)
NA
24501399
DrugRepV_4333N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.2 %)
NA
24501399
DrugRepV_43342-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (8.6 %)
NA
24501399
DrugRepV_4335N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (66.9 %)
NA
24501399
DrugRepV_4336N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (9.6 %)
NA
24501399
DrugRepV_43374-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (34 %)
NA
24501399
DrugRepV_4338N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (11.6 %)
NA
24501399
DrugRepV_4339N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (45.7 %)
NA
24501399
DrugRepV_4340N-(3-chlorophenyl)-N-(4-cyanophenyl)urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.1 %)
NA
24501399
DrugRepV_4341N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-3.4 %)
NA
24501399
DrugRepV_4342N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (5.7 %)
NA
24501399
DrugRepV_43434,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-24.6 %)
NA
24501399
DrugRepV_43441-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (13.1 %)
NA
24501399
DrugRepV_43452-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (6.4 %)
NA
24501399
DrugRepV_4346N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (6.2 %)
NA
24501399
DrugRepV_43472-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.7 %)
NA
24501399
DrugRepV_4348N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (2.1 %)
NA
24501399
DrugRepV_43494,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-0.6 %)
NA
24501399
DrugRepV_4350N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-2.6 %)
NA
24501399
DrugRepV_43513-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-6.1 %)
NA
24501399
DrugRepV_4352methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (82.4 %)
NA
24501399
DrugRepV_4353N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (33.4 %)
NA
24501399
DrugRepV_4354N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (25.4 %)
NA
24501399
DrugRepV_4355(1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (10.5 %)
NA
24501399
DrugRepV_43564-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (25.2 %)
NA
24501399
DrugRepV_4357N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (17.4 %)
NA
24501399
DrugRepV_43583-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (26.8 %)
NA
24501399
DrugRepV_43595-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-6.6 %)
NA
24501399
DrugRepV_43606-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (20.9 %)
NA
24501399
DrugRepV_43612-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-12.1 %)
NA
24501399
DrugRepV_4362N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (12.3 %)
NA
24501399
DrugRepV_43634-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (1.8 %)
NA
24501399
DrugRepV_43642-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (1.1 %)
NA
24501399
DrugRepV_43655-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-0.3 %)
NA
24501399
DrugRepV_43662-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-1.5 %)
NA
24501399
DrugRepV_43672-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-15.9 %)
NA
24501399
DrugRepV_4368N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-11.5 %)
NA
24501399
DrugRepV_43698-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (-11.7 %)
NA
24501399
DrugRepV_4370N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide
NA
NA
Ebola virus
GP, amino acids 196 to 205
NA
CatL-Peptide cleavage
Decrease (8.05 %)
NA
24501399
DrugRepV_4371N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (24.79 %)
NA
24501399
DrugRepV_4372N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (31.07 %)
NA
24501399
DrugRepV_43739H-carbazol-3-amine
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (8.2 %)
NA
24501399
DrugRepV_43747-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (37.87 %)
NA
24501399
DrugRepV_4375N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-0.67 %)
NA
24501399
DrugRepV_4376tris[4-(dimethylamino)phenyl]methanol
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (108.4 %)
NA
24501399
DrugRepV_43776-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (39.17 %)
NA
24501399
DrugRepV_43781-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (5.24 %)
NA
24501399
DrugRepV_43792-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-2.7 %)
NA
24501399
DrugRepV_4380N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (40.4 %)
NA
24501399
DrugRepV_43814-{[(5-methyl-2-thienyl)methyl]amino}phenol
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-14.4 %)
NA
24501399
DrugRepV_4382N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-7.77 %)
NA
24501399
DrugRepV_4383N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (0.34 %)
NA
24501399
DrugRepV_43842-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-9.26 %)
NA
24501399
DrugRepV_4385N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (73.49 %)
NA
24501399
DrugRepV_4386N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-4.08 %)
NA
24501399
DrugRepV_43874-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (7.92 %)
NA
24501399
DrugRepV_4388N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (42.12 %)
NA
24501399
DrugRepV_4389N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (32.88 %)
NA
24501399
DrugRepV_4390N-(3-chlorophenyl)-N-(4-cyanophenyl)urea
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (24.49 %)
NA
24501399
DrugRepV_4391N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (0.86 %)
NA
24501399
DrugRepV_4392N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (6.5 %)
NA
24501399
DrugRepV_43934,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-7.5 %)
NA
24501399
DrugRepV_43941-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (35.73 %)
NA
24501399
DrugRepV_43952-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-2.85 %)
NA
24501399
DrugRepV_4396N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (37.33 %)
NA
24501399
DrugRepV_43972-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (22.44 %)
NA
24501399
DrugRepV_4398N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (37.22 %)
NA
24501399
DrugRepV_43994,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (33.41 %)
NA
24501399
DrugRepV_4400N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (7.38 %)
NA
24501399
DrugRepV_44013-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-0.01 %)
NA
24501399
DrugRepV_4402methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (90.92 %)
NA
24501399
DrugRepV_4403N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (12.1 %)
NA
24501399
DrugRepV_4404N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (21.93 %)
NA
24501399
DrugRepV_4405(1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-8.72 %)
NA
24501399
DrugRepV_44064-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (17.7 %)
NA
24501399
DrugRepV_4407N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (23.22 %)
NA
24501399
DrugRepV_44083-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (23.55 %)
NA
24501399
DrugRepV_44095-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (3.55 %)
NA
24501399
DrugRepV_44106-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (32.65 %)
NA
24501399
DrugRepV_44112-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (3.23 %)
NA
24501399
DrugRepV_4412N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (25.12 %)
NA
24501399
DrugRepV_44134-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-11.51 %)
NA
24501399
DrugRepV_44142-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (5.7 %)
NA
24501399
DrugRepV_44155-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-10.47 %)
NA
24501399
DrugRepV_44162-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-2.95 %)
NA
24501399
DrugRepV_44172-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-9.09 %)
NA
24501399
DrugRepV_4418N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-0.72 %)
NA
24501399
DrugRepV_44198-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (-10.37 %)
NA
24501399
DrugRepV_4420N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide
NA
NA
Hendra virus
F0, amino acids 105 to 114
NA
CatL-Peptide cleavage
Decrease (3.26 %)
NA
24501399
DrugRepV_4421N-(1,3-benzodioxol-5-ylmethyl)-2-(3-cyano-2-methyl-1H-indol-1-yl)acetamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (91.98 %)
NA
24501399
DrugRepV_4422N-benzyl-6-phenyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (98.65 %)
NA
24501399
DrugRepV_44239H-carbazol-3-amine
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (42.29 %)
NA
24501399
DrugRepV_44247-(1H-benzimidazol-2-ylthio)-8-methyl[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (60.65 %)
NA
24501399
DrugRepV_4425N-[2-(2-methoxyethyl)-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazol-8-yl]benzamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (-0.15 %)
NA
24501399
DrugRepV_4426tris[4-(dimethylamino)phenyl]methanol
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (82.15 %)
NA
24501399
DrugRepV_44276-chloro-N-[3-(4-methyl-1H-pyrazol-1-yl)propyl]-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (88.99 %)
NA
24501399
DrugRepV_44281-(2-furoyl)-5-(2-furyl)-3-(3-methoxyphenyl)-4,5-dihydro-1H-pyrazole
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (24.06 %)
NA
24501399
DrugRepV_44292-[(1H-benzimidazol-2-ylmethyl)thio]-1-[2-(4-methylphenoxy)ethyl]-1H-benzimidazole
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (57.39 %)
NA
24501399
DrugRepV_4430N-(3-chloro-4-fluorophenyl)-N-[4-(4-morpholinylsulfonyl)phenyl]urea
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (77.83 %)
NA
24501399
DrugRepV_44314-{[(5-methyl-2-thienyl)methyl]amino}phenol
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (1.34 %)
NA
24501399
DrugRepV_4432N-[5-(1H-benzimidazol-2-yl)-2-methylphenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (76.53 %)
NA
24501399
DrugRepV_4433N-[1-benzyl-2-oxo-2-(4-phenyl-1-piperazinyl)ethyl]benzamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (14.51 %)
NA
24501399
DrugRepV_44342-methoxy-N-[1-methyl-2-(1-pyrrolidinylmethyl)-1H-benzimidazol-5-yl]benzamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (8.55 %)
NA
24501399
DrugRepV_4435N-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-2-(2-naphthyloxy)acetamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (79.93 %)
NA
24501399
DrugRepV_4436N-(2,5-dimethoxyphenyl)-N-[4-(trifluoromethyl)phenyl]urea
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (69.24 %)
NA
24501399
DrugRepV_44374-{[(1H-benzimidazol-2-ylthio)acetyl]amino}phenyl thiocyanate
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (65.51 %)
NA
24501399
DrugRepV_4438N-(3,4-dichlorophenyl)-N-[3-(trifluoromethyl)phenyl]urea
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (80.76 %)
NA
24501399
DrugRepV_4439N-1,3-benzodioxol-5-yl-6-chloro-2-(3-pyridinyl)-4-quinolinecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (65.73 %)
NA
24501399
DrugRepV_4440N-(3-chlorophenyl)-N-(4-cyanophenyl)urea
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (78.34 %)
NA
24501399
DrugRepV_4441N-[4-(1H-benzimidazol-2-yl)phenyl]-2-chloro-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (52.46 %)
NA
24501399
DrugRepV_4442N-[3-(aminocarbonyl)-5-benzyl-2-thienyl]-2-methyl-3-furamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (24.34 %)
NA
24501399
DrugRepV_44434,5-dimethyl-2-{[(5-propyl-3-thienyl)carbonyl]amino}-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (39.61 %)
NA
24501399
DrugRepV_44441-(isopropylamino)-3-(3-phenyl-4,5-dihydropyrazolo[4,3-a]carbazol-10(3H)-yl)-2-propanol
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (44.31 %)
NA
24501399
DrugRepV_44452-[(4-tert-butyl-1,3-thiazol-2-yl)amino]-8-quinolinol
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (38.88 %)
NA
24501399
DrugRepV_4446N-(aminocarbonyl)-2-{[(5-methyl-3-thienyl)carbonyl]amino}-3-thiophenecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (38.54 %)
NA
24501399
DrugRepV_44472-chloro-N-(4-phenyl-1,3-thiazol-2-yl)-5-(4H-1,2,4-triazol-4-yl)benzamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (50.22 %)
NA
24501399
DrugRepV_4448N-[3-(2-oxo-2H-chromen-3-yl)phenyl]-1,3-benzodioxole-5-carboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (51.28 %)
NA
24501399
DrugRepV_44494,5-dimethyl-2-[(phenoxyacetyl)amino]-N-(3-pyridinylmethyl)-3-thiophenecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (39.55 %)
NA
24501399
DrugRepV_4450N-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}phenyl)-1-benzothiophene-3-carboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (33.84 %)
NA
24501399
DrugRepV_44513-[(1H-benzimidazol-2-ylmethyl)thio]-9-benzyl-9H-[1,2,4]triazolo[4,3-a]benzimidazole
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (23.55 %)
NA
24501399
DrugRepV_4452methyl N-[4,6-bis(isopropylamino)-1,3,5-triazin-2-yl]-N-cyanoglycinate
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (77.79 %)
NA
24501399
DrugRepV_4453N-(3,4-dichlorophenyl)-2-oxo-2,3-dihydro-1,3-benzoxazole-6-sulfonamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (56.45 %)
NA
24501399
DrugRepV_4454N-(3-pyridinylmethyl)dibenzo[b,d]furan-3-amine
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (47.55 %)
NA
24501399
DrugRepV_4455(1,3-benzodioxol-5-ylmethyl)[4-(1-pyrrolidinyl)phenyl]amine
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (-3.09 %)
NA
24501399
DrugRepV_44564-methyl-5-phenyl-N-3-pyridinyl-2-thiophenecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (72.37 %)
NA
24501399
DrugRepV_4457N-(2,5-dimethoxyphenyl)-2-(2-oxo-1,3-benzoxazol-3(2H)-yl)acetamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (47.94 %)
NA
24501399
DrugRepV_44583-[(2,4-dichlorophenoxy)methyl]-N-(3-pyridinylmethyl)benzamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (53.23 %)
NA
24501399
DrugRepV_44595-phenyl-2-(2-phenylethyl)[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (28.07 %)
NA
24501399
DrugRepV_44606-bromo-2-oxo-N-3-pyridinyl-2H-chromene-3-carboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (25.6 %)
NA
24501399
DrugRepV_44612-[(2-methyl-8-quinolinyl)amino]-4H-pyrido[3,2-e][1,3]thiazin-4-one
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (37.16 %)
NA
24501399
DrugRepV_4462N-(3-chloro-4-fluorophenyl)-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]urea
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (61.47 %)
NA
24501399
DrugRepV_44634-({[(3-chloro-4-fluorophenyl)amino]carbonyl}amino)-N-methylbenzenesulfonamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (66.62 %)
NA
24501399
DrugRepV_44642-(4-fluorophenyl)-N-(4-{[(4-methylphenyl)amino]sulfonyl}phenyl)acetamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (32.44 %)
NA
24501399
DrugRepV_44655-methyl-N-[4-(1-pyrrolidinylsulfonyl)phenyl]-3-thiophenecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (30.53 %)
NA
24501399
DrugRepV_44662-amino-N-(3-chlorophenyl)-3-quinolinecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (47.39 %)
NA
24501399
DrugRepV_44672-(1,3-benzodioxol-5-yl)-1-(1,3-benzodioxol-5-ylmethyl)-1H-benzimidazole
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (49.81 %)
NA
24501399
DrugRepV_4468N-{3-[(benzylamino)carbonyl]phenyl}-5-methyl-3-thiophenecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (51.17 %)
NA
24501399
DrugRepV_44698-chloro-N-[3-(3-methyl-1H-pyrazol-1-yl)propyl]-2-(2-pyridinyl)-4-quinolinecarboxamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (41.66 %)
NA
24501399
DrugRepV_4470N-[4-(2,4-difluorophenyl)-1,3-thiazol-2-yl]-2-(2-thienyl)acetamide
NA
NA
Severe acute respiratory syndrome coronavirus
S, amino acids 674 to 683
NA
CatL-Peptide cleavage
Decrease (40.85 %)
NA
24501399